1510s Full title "Cartoon: The Virgin and Child with Saint John Baptist and Saint Anne(?)" Black chalk, heightened with white, on paper; not pricked for transfer to panel, 141.5x104.6 cm
Perhaps drawn in the mid-1490s. Later (in 1500-01) Leonardo made another cartoon (now lost) of the Virgin and Child with Saint Anne.
A painting by Leonardo of similar subject but differnet deisgn (and clearly later in date) is in the Louvre. A painted variant of the picture, by Luini, is in the Ambrosiana in Milan.
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